Transformative pain therapeutics

Changing the course of pain for patients who need it most

Who we are

Adynxx, located in San Francisco, California, is a clinical-stage biotechnology company developing a transformative technology platform addressing pain at its molecular roots. Adynxx’s unique approach is to transform pain management by approaching pain as a disease rather than a symptom.

Therapeutic approach

Provide safe, non-opioid, long-term pain reduction with a single administration

Clear mission

Developing transformative, first-in-class therapies to address significant unmet medical needs

Groundbreaking Science

A proprietary platform of non-opioid, disease-modifying oligonucleotide therapeutics

Tackling high unmet need

Focusing on patients who have the greatest need for innovative pain treatments

News & Publications

Apr 12, 2018
SAN FRANCISCO, April 12, 2018 – Adynxx Inc., a clinical stage biotechnology company developing a novel platform of first-in-class, disease-modifying, non-opioid pain therapeutics, today announced Phase 2 study results of its lead therapeutic candidate, brivoligide (AYX1) for the treatment of post-surgical pain. The ADYX-004 trial assessed safety and efficacy of a single preoperative dose of brivoligide compared to placebo in 210 subjects undergoing unilateral total knee arthroplasty where all subjects also received standard perioperative pain management.

Meet our team

Experienced management team with a proven track record of success dedicated to improving the life of patients